Leonard J. Mueller
Assistant Professor
Physical Chemistry
B.S., 1988, University of Rochester
C.P.G.S., 1989, University of Cambridge
Ph.D., 1997, California Institute of Technology
ACS Postdoctoral Fellow, 1996-98, Massachusetts Institute of Technology
Research Interests:
My group at UC Riverside has developed a diverse physical chemistry research program unified through applications of nuclear magnetic resonance (NMR). There are now three distinct research directions in my group encompassing the following areas: (1) Structure and Dynamics with Solid-State NMR: emphasizing the development of novel experimental and theoretical methods; (2) Dynamic NMR: a quantum-statistical treatment of chemical exchange and new applications to kinetic and thermodynamic studies of small molecules in solution and gas phases; and (3) New Physics in NMR: quantum computing in the solid state with single crystal NMR.
Professional Experience:
Selected Publications
Reinstra, C. M.; Hatcher, M. E.; Mueller, L. J.; Sun, B.; Feski, S. W.; Griffin, R. G. "Efficent Multispin Homonuclear Double-Quantum Recoupling Magic-Angle Spinning NMR: 13C-13C Correlation Spectroscopy of U-13C-Erythromycin A," J. Am. Chem. Soc. 1998, 120, 10602-10612.
Mueller, L. J.; Weitekamp, D. P. "Quantum-Statistical Corrections to Dynamic Nuclear Magnetic Resonance," Science 1999, 283, 61-65.
Reed, C. A.; Kim, K-C.; Bolskar, R. D.; Mueller, L. J. "Taming Superacids: Stabilization of Fullerene Cations HC60+ and C60+," Science 2000, 289, 101-104.
Okamura, W. H., Zhu, G-D.; Hill, D. K.; Thomas, R. J.; Ringe, K.; Borchardt, D. B.; Norman, A. W.; Mueller, L. J. "Synthesis and NMR Studies of 13C Labeled Vitamin D Metabolites," J. Org. Chem. 2002, 67(5), 1637-1650.
Mueller, L. J.; Elliott, D. W.; Kim, K-C.; Reed, C. A.; Boyd, P. D. W. "Establishing Through-Bond Connectivity in Solids with NMR: Structure and Dynamics in HC60+," J. Am. Chem. Soc. 2002, 124, 9360-9361.
Kim, K-C.; Reed, C. A.; Elliott, D. W.; Mueller, L. J.; Tham, F.; Lin, L.; Lambert, J. B. "Crystallographic Evidence for a Free Silylium Ion," Science 2002, 297, 825-827.
Reinstra, C. M.; Hohwy, M.; Mueller, L. J.; Jaroneic, C. P.; Reif, B.; Griffin, R. G. "Determination of Multiple Torsion-Angle Constraints in U-15N-13C-Labeled Peptides: 3D-1H-15N-13C-1H Dipolar Chemical Shift NMR Spectroscopy in Rotating Solids," J. Am. Chem. Soc. 2002, 124(40), 11908-11922.
Reed, C. A.; Kim, K-C.; Stoyanov, E. S.; Stasko, D.; Tham, F. S.; Mueller, L. J.; Boyd, P. D. W. "Isolating Benzenium Ion Salts," J. Am. Chem. Soc. 2003, 125(7), 1796-1804.
Mueller, L. J.; Elliott, D. W. "Correlated Tensor Interactions and Rotational-Echo Double-Resonance of Spin Clusters," J. Chem. Phys. 2003, 118(19), 8873-8881.
Leskowitz, G. M.; Olsen, R. A.; Ghaderi, N.; Mueller, L. J. "Three-Qubit NMR Quantum Information Processing with a Single-Crystal Solid," J. Chem. Phys. 2003, 119(3), 1643-1649.
Olsen, R. A.; Liu, L.; Ghaderi, N.; Johns, A.; Hatcher, M. E.; Mueller, L. J. "The Amide Rotational Barriers in Picolinamide and Nicotinamide: NMR and Ab Initio Studies," J. Am. Chem. Soc. 2003, 125(33), 10125-10132.
Olsen, R. A.; Struppe, J.; Elliott, D. W.; Mueller, L. J. "Through-Bond 13C-13C Correlation at the Natural Abundance Level: Refining Dynamic Regions in the Crystal Structure of Vitamin-D3 with Solid-State NMR," J. Am. Chem. Soc. 2003, in press, 3 manuscript pages.
WWW: Research
Email: leonard.mueller@ucr.edu
Extension: 3565
Assistant Professor
Physical Chemistry
B.S., 1988, University of Rochester
C.P.G.S., 1989, University of Cambridge
Ph.D., 1997, California Institute of Technology
ACS Postdoctoral Fellow, 1996-98, Massachusetts Institute of Technology
Research Interests:
My group at UC Riverside has developed a diverse physical chemistry research program unified through applications of nuclear magnetic resonance (NMR). There are now three distinct research directions in my group encompassing the following areas: (1) Structure and Dynamics with Solid-State NMR: emphasizing the development of novel experimental and theoretical methods; (2) Dynamic NMR: a quantum-statistical treatment of chemical exchange and new applications to kinetic and thermodynamic studies of small molecules in solution and gas phases; and (3) New Physics in NMR: quantum computing in the solid state with single crystal NMR.
Professional Experience:
Selected Publications
Reinstra, C. M.; Hatcher, M. E.; Mueller, L. J.; Sun, B.; Feski, S. W.; Griffin, R. G. "Efficent Multispin Homonuclear Double-Quantum Recoupling Magic-Angle Spinning NMR: 13C-13C Correlation Spectroscopy of U-13C-Erythromycin A," J. Am. Chem. Soc. 1998, 120, 10602-10612.
Mueller, L. J.; Weitekamp, D. P. "Quantum-Statistical Corrections to Dynamic Nuclear Magnetic Resonance," Science 1999, 283, 61-65.
Reed, C. A.; Kim, K-C.; Bolskar, R. D.; Mueller, L. J. "Taming Superacids: Stabilization of Fullerene Cations HC60+ and C60+," Science 2000, 289, 101-104.
Okamura, W. H., Zhu, G-D.; Hill, D. K.; Thomas, R. J.; Ringe, K.; Borchardt, D. B.; Norman, A. W.; Mueller, L. J. "Synthesis and NMR Studies of 13C Labeled Vitamin D Metabolites," J. Org. Chem. 2002, 67(5), 1637-1650.
Mueller, L. J.; Elliott, D. W.; Kim, K-C.; Reed, C. A.; Boyd, P. D. W. "Establishing Through-Bond Connectivity in Solids with NMR: Structure and Dynamics in HC60+," J. Am. Chem. Soc. 2002, 124, 9360-9361.
Kim, K-C.; Reed, C. A.; Elliott, D. W.; Mueller, L. J.; Tham, F.; Lin, L.; Lambert, J. B. "Crystallographic Evidence for a Free Silylium Ion," Science 2002, 297, 825-827.
Reinstra, C. M.; Hohwy, M.; Mueller, L. J.; Jaroneic, C. P.; Reif, B.; Griffin, R. G. "Determination of Multiple Torsion-Angle Constraints in U-15N-13C-Labeled Peptides: 3D-1H-15N-13C-1H Dipolar Chemical Shift NMR Spectroscopy in Rotating Solids," J. Am. Chem. Soc. 2002, 124(40), 11908-11922.
Reed, C. A.; Kim, K-C.; Stoyanov, E. S.; Stasko, D.; Tham, F. S.; Mueller, L. J.; Boyd, P. D. W. "Isolating Benzenium Ion Salts," J. Am. Chem. Soc. 2003, 125(7), 1796-1804.
Mueller, L. J.; Elliott, D. W. "Correlated Tensor Interactions and Rotational-Echo Double-Resonance of Spin Clusters," J. Chem. Phys. 2003, 118(19), 8873-8881.
Leskowitz, G. M.; Olsen, R. A.; Ghaderi, N.; Mueller, L. J. "Three-Qubit NMR Quantum Information Processing with a Single-Crystal Solid," J. Chem. Phys. 2003, 119(3), 1643-1649.
Olsen, R. A.; Liu, L.; Ghaderi, N.; Johns, A.; Hatcher, M. E.; Mueller, L. J. "The Amide Rotational Barriers in Picolinamide and Nicotinamide: NMR and Ab Initio Studies," J. Am. Chem. Soc. 2003, 125(33), 10125-10132.
Olsen, R. A.; Struppe, J.; Elliott, D. W.; Mueller, L. J. "Through-Bond 13C-13C Correlation at the Natural Abundance Level: Refining Dynamic Regions in the Crystal Structure of Vitamin-D3 with Solid-State NMR," J. Am. Chem. Soc. 2003, in press, 3 manuscript pages.
WWW: Research
Email: leonard.mueller@ucr.edu
Extension: 3565